Pharmacology-1 available questions for Pabna University of Science and Technology:
[PUST-2018, PUST-2017]
[If you have any semester final exam questions for this course, please send them to this WhatsApp number: 01325972889. I will upload them to the database.]
[PUST-2018] Pharmacology-1
Define prodrug. "Prodrug is intended to improve the ADME of the drug"- explain the statement with examples.
Enumerate the advantages and disadvantages of oral and buccal route of drug administration.
Give a brief discussion on types, symptoms and treatment of drug toxicity.
Write down the symptoms and possible treatment options of drug dependence.
Differentiate drug abuse from drug dependence.
Enumerate the various factors affecting drug distribution.
What do you mean by analgesic-antipyretic drug? Give the classification of it.
Describe the pharmacological actions and side effects of Nonsteroidal anti-inflammatory drugs (NSAIDs).
Point out the use and adverse effect of acetylsalicylic acid.
Write down the pharmacokinetics of morphine.
Illustrate the various depressant actions of morphine and its cogeners.
How can you differentiate between morphine and pethidine?
Write short note on-
(i) Ibuprofen
(ii) Etoricoxib.
Briefly describe various stages of sleep cycle.
Give a brief discussion on the pharmacological actions of barbiturates.
Write short note on the followings -
(i) Alprazolam
(ii) Amphetamines.
Write down the uses of H1, and H2 histamine blockers.
Write down the pharmacological and physiological role of histamine in the body.
What is antihistamine? Why H1 second generation antihistamine is preferred to a first generation?
Write down the synthesis of 5-HT.
How gastric acid secretions are regulated within the body?
Define Proton Pump Inhibitor (PPI). How do PPI inhibit the secretion of HCI?
Point out possible drug interactions with antacids.
Why antacid combinations are superior to single antacid agent? Give examples.
Define anesthesia. Briefly discus the different stages of anesthesia.
Enumerate the mechanism of action, pharmacological effect and toxicities of local anesthetics.
How does enflurane work as general anesthetic agent?
[PUST-2017] Pharmacology-1
Define therapeutic window. What information you get from drugs therapeutic window?
Write shortly on sublingual and subcutaneous routes of drug administration with their respective advantages and disadvantages.
Define the following terms-
Loading dose
Posology
Superagonist
Selective agonist
What do you mean by drug synergism? Give at least two examples of drug synergism.
Drug tolerance is basically the body's ability to adapt to the presence of a drug- Explain.
Describe the treatment, sign and symptoms of drug dependence.
What do you mean by acute morphine poisoning? Give its sign and symptoms.
How paracetamol develops liver and kidney toxicity? Give its possible treatment options.
Enumerate the pharmacological actions of aspirin on
Acid-base and electrolyte balance
Metabolism
Blood
Gastrointestinal tract.
Describe the therapeutic effects and adverse effects of barbiturates.
Illustrate in brief the pharmacokinetics and pharmacological actions of caffeine.
Write short note on-
Ketorolac
Diazepam
What are anti-histamines? Classify the anti-histamines.
Differentiate between H1 and H2 receptor blockers.
Define prostaglandin. How prostaglandin bio-synthesized in human body?
Write down the synthesis, storage and destruction of serotonin.
Briefly describe the functions and pharmacology of kallikreins and kinins.
Mention the therapeutic uses of prostaglandins.
Point out the functions of PGE2 and PGI2.
What are local anesthetics? Classify it with suitable examples.
Narrate the mechanisms of action of local anesthetics.
Describe the pharmacological action, clinical uses and fate of lidocaine.
Mention various approaches for the treatment of peptic ulcer.
What is anticholinergics? Write down the functions of pirenzepine.
What are the special considerations of aluminum carbonate?
Why are Al(OH)3 and Mg(OH)2 combination used in market preparation of gastric antacid?
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