Pharmacology-1 available questions for Comilla University: [CoU-2019, CoU-2017]
Pharmacology-2 available questions for Comilla University: [CoU-2020]
[CoU-2020] Pharmacology 2
Explain the chemistry of insulin.
How can insulin resistance be developed? Write down the symptoms and treatment of insulin resistance.
State the mechanism of action of insulin. Differentiate between diabetes and hyperglycemia.
Mention the symptoms and treatment of morphine poisoning.
Compare and contrast between morphine and indomethacin.
Write down the mechanism of action and drug interaction of Streptomycin.
What is saddle block? Differentiate between local and general anesthetics.
Describe the stages and planes of anesthesia.
Illustrate the necessity of preanesthetic medication. State the mechanism of action of general anesthetics. Write down the advantages and disadvantages of halothane.
Elucidate the method of bacterial growth inhibition of cotrimoxazole.
How can superinfection be developed? Write down the treatment process of superinfection.
Compare and contrast between penicillin and cephalosporin.
Briefly describe the action potential of cardiac muscles.
How does histamine work?
Write down the mechanism of action and adverse effects of ACE inhibitors.
Write down the biosynthesis of prostaglandins.
How does sulphonylurea reduce hyperglycemia? Point out its adverse effects and contraindication.
Mention the pharmacological effects of 5-HT.
How can you classify antihypertensive drugs?
State the possible causes, risk factors and treatment of atherosclerosis.
How captopril works?
Mention possible side effects of vasodilators.
Write down the mechanism and adverse effects of loop diuretics.
How can penicillin act as an antimicrobial agent.
Write down short notes on
Fanconi syndrome
Gray baby syndrome
[CoU-2019] Pharmacology-1
What are the possible routes of administration of a drug? Name the factors governing the choice of a route.
How a drug is absorbed in the body? What are the contributing factors of drug absorption process?
Define protein binding. What are the clinical significances of protein binding?
Briefly describe all the possible phase I and phase II reactions of drug metabolism process.
Define coagulation. Describe the common pathway of blood coagulation.
Write down the mechanism of actions of clopidogrel and coumarin.
What is GPCR? Draw and discuss the structure of a GPCR. How do GPCRs exhibit drug effect?
How signaling via ligand and voltage gated channels occurs?
What is Peptic ulcer disease (PUD)? What are the causes and treatment strategy of PUD?
What is the recent warning of Ranitidine use in Bangladesh?
Draw a comparative table highlighting the pharmacokinetic parameters of PPIs.
How gastric acid secretion is regulated?
Illustrate the life cycle of malarial parasite.
List down the therapeutic effects and adverse effects of BDZs.
Discuss about different mechanisms of drug action.
Mention the mechanism of action of heparin and warfarin.
Outline the measures for the treatment of barbiturate poisoning.
How does metronidazole work as anti-amoebic drug?
Explain enzyme induction with example.
Discuss about the role of prostaglandin analogue for peptic ulcer..
Write a short note on rebound acidity.
[CoU-2017] Pharmacology-1
Mention the factors influence choice of drug administration in different routes.
How drugs are -
Penetrating into brain and CSF?
Passage across placenta?
What is drug metabolism? Give the different synthetic reactions of drug metabolism.
Write the different processes of excretion of drugs and their metabolites.
Differentiate between adverse effects and side effects.
Define-
Agonist
Inverse agonist
Partial agonist
Give the basic evidence for drug action through receptors.
Describe the mechanism of G-protein coupled receptors with neat sketch diagram.
Define dose. Give the advantages and disadvantages of fixed dose combination of drugs.
What is rational use of medicines?
Define-
Idiosyncrasy
Teratogenicity
Define peptic ulcer. Give the different approaches for the treatment of peptic ulcers.
Write the mechanism, pharmacokinetics and drug interaction of H2 antagonists.
Why antacid combinations are superior to any single antacid?
Define haematinics. Give the process of transport, utilization, storage and excretion of Iron.
What is erythropoietin? Write its use and adverse effects.
Give the mechanism of actions and pharmacokinetics of heparin.
Write down the mechanism of action of barbiturates.
Why doctors generally prefer benzodiazepines compared to barbiturates?
Give differences between sedatives and hypnotics.
Classify the antimalarial drugs. Give the treatment of severe and complicated falciparum malaria based on WHO guidelines.
Mention the uses of metronidazole in different infections.
Give the choice of drugs for helminthiasis. Write the uses of albendazole.
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