Pharmacology-1 available questions for Bangabandhu Sheikh Mujibur Rahman Science and Technology University: [BSMRSTU-2018]
Pharmacology-2 available questions for Bangabandhu Sheikh Mujibur Rahman Science and Technology University: [BSMRSTU-2019, BSMRSTU-2018,
BSMRSTU-2017]
[If you have any semester final exam questions for this course, please send them to this WhatsApp number: 01325972889. I will upload them to the database.]
[BSMRSTU-2019] Pharmacology 2
State the following terms:
Inverse agonist
Partial agonist
Therapeutic index
Define dose response curve? How could you calculate the dose of an oral formulation?
What is false transmitter? State the signal transduction pathway of nuclear receptor.
Describe the signaling mechanism of G protein coupled receptor.
State the mechanism of action, indication and adverse effects of Ceftriaxone.
What are the manifestations of Penicillin induced hypersensitivity? How can these be managed?
Explain the rationale for the combination of Amoxicillin with Clavulanic acid.
Write short note on "Superinfection".
Define Quinolones. State the mechanism of action and side effects of Ciprofloxacin.
Write down the mechanism of action and therapeutic uses of Aminoglycosides.
Explain why Tetracycline should not be given to child?
Write short note on "Fanconi's syndrome".
"Where there is no acetylcholine there is no nor-adrenaline"- justify the statement.
What is Physostigmine? How does acetylcholine esterase work?
State the role of voltage sensitive calcium channel in acetylcholine release? How does acetylcholine cause smooth muscle relaxation?
Write the pharmacological action and therapeutic uses of Epinephrine.
State the pharmacological actions of adrenoceptor agonists on vascular smooth muscles.
Shortly narrate the mechanism of action of Organophosphorus compounds.
Mention the pharmacological effects of Atropine. What are the therapeutic uses of Prazosin?
Evaluate the role of nicotinic antagonists as ganglionic blockers.
What is the role of tyrosine hydroxylase in adrenergic neuron synthesis?
Is Carbachol a muscarinic agonist? Mention the therapeutic uses of Carbachol.
Why does Spironolactone used in combination with Thiazide or Loop diuretics?
"Loop diuretics are called high ceiling diuretics", explain. Mention the adverse effects of Loop diuretics.
What is depression? Classify antidepressants with example.
Define SSRI. Illustrate the mechanism of action of SSRI.
Vindicate the mechanism of action and side effects of TCA.
Define neurosis? Write down the indications, toxicity and contraindication of Chlorpromazine.
[BSMRSTU-2018] Pharmacology-1
What is pharmacology? How does it differ from pharmacopoeia?
Define drug. What is the difference between drug and medicine?
With example, name the different routes of drug administration.
Define biological drug. What is it's characteristic?
Mention the therapeutic uses and adverse effects of barbiturates.
Write down the mechanism of action and pharmacology of Benzodiazepines.
Justify, benzodiazepine is better hypnotic than barbiturate.
Write a note on dose response relationship?
Define and classify receptor. Name four common receptors with their agonist and antagonists.
What are the different mechanisms of drug action? Discuss about the cellular mechanism of dr action.
Explain the physiological role and therapeutic uses of prostaglandins?
Classify and enumerate antihistamines?
Discuss the synthetic pathway of prostaglandins. Mention the physiological role of prostaglandins
Define and classify epilepsy.
Discuss the mode of action and adverse effect of Phenytoin.
What is the pharmacological rationale in using L-dopa and carbi-dopa in sane formulation?
Define haematinic. What are the different iron preparations?
Write down the manifestations and management of acute Iron poisoning.
How does Heparin act? What are the indications of Heparin-therapy?
Classify and enumerate in vitro and in vivo anticoagulants.
*What are the mechanismas that account for the transfer of drug(other solute).
With examples,name the different routes of drug administration.
Explain the factors governing route on administration with examples?
Write a note on factors governing passive diffusion of drugs?
Differentiate between narcotic and non-narcotic analgesics.
Classify opiates. Depict the M/A and therapeutic uses of morphine.
What is low dose aspirin? How low dose aspirin prevent thromboembolism?
Classify NSAIDs with example. Why selective COX-2 inhibitors are less likely to produce gastric ulceration.
[BSMRSTU-2018] Pharmacology 2
State the following terms:
Inverse agonist
Antagonist
Therapeutic window
Define dose response curve? Draw and explain the typical AUC layout of an oral formulation.
Classify receptor based on the mechanism. Illustrate the mechanism of kinase linked receptor.
Define second messenger. Describe the mechanism of G protein coupled receptor.
Define antibiotics. Classify antibiotics based on the mechanism of action with examples.
State the mechanism of action, indication and adverse effects of penicillin.
What are the manifestations of penicillin induced hypersensitivity? How can these be managed?
Write a short note on "Gray Baby Syndrome"
Define Macrolides. State the mechanism of action and side effects of Azithromycin.
Write down the mechanism of action of sulphonamides & co-trimoxazole.
Define broad spectrum antibiotics. Classify cephalosporin antibiotics with example.
Illustrate the mechanism of bacterial resistance to antibiotics.
"Where there is no acetylcholine there is no nor-adrenaline"- justify the statement.
What are the catecholamines? Why are they called so? Mention the important pharmacological actions of adrenaline and nor-adrenaline.
State the pharmacological effects of acetylcholine.
How does organophosphorus compound act as anti-cholinesterase?
Define and classify adrenoceptors with example.
Illustrate the site and mechanism of atropine action and how can it be resort? us
Define Ganglion blockers? How do they exert their action?
Write a short note on "Myasthenia gravis".
Define and classify diuretics with example.
Write down the mechanism of action, indication and side effects of high ceiling diuretics.
How do carbonic anhydrase inhibitors act as diuretics?
Why is spironolactone called K+ sparing diuretics?
Classify antimicrobials that can be used in fungal infection.
What are the advantages of fluconazole over ketokonazole?
What is superficial infection? Sate the therapeutic use and adverse effects of Griseofulvin.
How does Amphotericin B exhibit its anti-fungal action?
Why benzodiazepines are considered safer than barbiturates?
What is MAOI? Write down the pharmacological effects and adverse reactions of MAOI.
Distinguish between sedative and hypnotics.
Enunciate different obstacles faced during treating depression.
[BSMRSTU-2017] Pharmacology-2
"Carbachol is a para sympathomimetic agent"-explain.
Differentiate between sympathetic and para sympathetic nervous system. How is signal transmitted from brain to effector organ?
Write the pharmacological uses of epinephrine and norepinephrine.
What is anticholinesterase? What are the roles of nicotine on ganglionic system?
What do you mean by Raynaud's syndrome? How does Acetylcholine alter vasoldilatory effect?
Shortly narrate the mode of action of organophosphorus compounds. Write the clinical uses of Atropine sulfate and Edrophonium.
How does muscarinic receptor work? Mention the functions of B-blockers.
Define and classify agonist with example. Mention the importance of therapeutic index.
What is drug receptor complex? Illustrate the relationship between drug reactivity and drug receptor bonds.
What is dose response relationship? Distinguish between potency and efficacy.
What do you mean by grey baby syndrome? Write the structure activity relationship classification of sulpha drug.
Write the mode of action and precaution of tetracycline therapy.
What is anti-fungal drug? Mention the indications and adverse effects of griseofulvin and ketoconazole.
Write down the sources of aminoglycoside and macrolide antibiotics with their chemical structure.
Distinguish between penicillin and cephalosporin. Mention the therapeutic use of ciprofloxacin.
Describe the mechanism of bacterial resistance against penicillin.
What is antibiotic resistance? How does resistance develop?
What is super infection? Outline the principles of combined use of antimicrobials.
Define bacteriocin with example? How do glycopeptide antibiotics exert their action?
What do you understand by Psychosis? Differentiate between organic and functional psychosis.
What do you understand by schizophrenia? Briefly describe the clinical features of schizophrenia.
Classify Psychotropic drugs with suitable example.
Briefly describe why diuretic drugs are prescribed for the maintenance of hypertension?
What are the rationales of using diuretic combination?
Write down the mechanism of action of k-sparing diuretics.
0 Comments