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[IU-2020] Pharmaceutics-1
Define preformulation? Why it is done? [IU-2020]
'Pro-drug synthesis and salt formation are two important approaches during preformulation studies'- justify. [IU-2020]
Calculate the amount of aspirin required 500 ml of a 0.9 % solution. [IU-2020]
What do you mean by hygroscopicity and how is measured ? Write down its importance in pharmaceuticals. [IU-2020]
Show the relationship between pH and pKa for acidic and basic drugs. Explain its significance on drug solubility and absorption. [IU-2020]
Prepare 1000 grams of dil. Acetic acid from acetic acid B. P. 33 % and 6 % w/w using allegation method. [IU-2020]
Define excipients. Mention the ideal properties and functions of excipients. [IU-2020]
Detail the classification of excipients with examples. [IU-2020]
Mention the functionality related characteristics of disintegrants and their potential impact in an oral solid dosage form. [IU-2020]
Discuss the method of preparation for 600 ml of alcohol from 95 % alcohol. [IU-2020]
What are organoleptic additives? Write down the sources of coloring and flavoring agents with examples. [IU-2020]
Differentiate between lubricants and glidants. [IU-2020]
Write down the classification and mode of action of surfectants. [IU-2020]
Convert the followings: 550 mg into grains, 1 table spoonful into ml and 1 grain to mg. [IU-2020]
Define the following terms with respect to the pharmaceutical products at least one example of each- i ) Polymer ii ) Repeating unit iii ) Homo polymer iv ) Vinyl monomer [IU-2020]
Mention at least four macromolecules as well as polymers? [IU-2020]
Distinguish between simple molecule and polymer molecule. [IU-2020]
Write the structural formula of the following high polymers and their corresponding monomer structure:
i ) Starch; ii ) Chitin; iii ) Nylon 6, 10 ; iv ) Natural silk [IU-2020]
Write the uses of the following macromolecules:
i ) Teflon ii ) Terylene [IU-2020]
What do you mean by radical? Write the structural formula and radical formulation from the following initiators :
i ) AVA ii ) CPO iii ) TBHPO [IU-2020]
Write the international recycling code of the following polymers ? ii ) HDPE iii ) PET iv ) LDPE v ) PVC i ) PSt vi ) PP [IU-2020]
Derive the equation of 'number average molecular weight ( Mn )' 'weight average molecular weight ( Mw )' of polymers. [IU-2020]
Write short note on:
(i) Carr's index and Hausner ratio
(ii) Angle of repose
(iii) Partition affinity on drug transport [IU-2020]
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